With reference to ISO 17025 governing testing and calibrating laboratories, laboratory shall use validated method. Method validation is the process of evaluating the performance of a test method to determine whether it is capable of producing test results that are fit for a particular purpose. During validation process the following parameter shall be performed such as:

1.      Precision

2.       Accuracy

3.      Limit of detection

4.      Limit of quantification

5.      Linearity

6.      Working range

7.      Robustness

8.      Ruggedness

9.      Sensitivity  

 References

1.      C. Burgess, Valid Analytical Methods and Procedures, Royal Society of Chemistry, Cambridge, 2000, ISBN 978-0-85404-482-5.

2.      Konieczka, Piotr. Quality assurance and quality control in the analytical chemical laboratory: a practical approach / Piotr Konieczka, Jacek Namiesnik.

3.      S.L R Ellison; V. J Barwick; T. J Duguid Farrant; Practical Statistics for the Analytical Scientist; A Bench Guide ;2^nd Edition